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United States National Library of Medicine
Industry: Library & information science
Number of terms: 152252
Number of blossaries: 0
Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) The relationships of groups of organisms as reflected by their genetic makeup. 2) The evolutionary history of a kind of organism. 3) The evolution of a genetically related group of organisms as distinguished from the development of the individual organism -- called also phylogenesis.
Industry:Health care
1) The repeating contractile units of the myofibril, delimited by Z bands along its length. 2) Any of the repeating structural units of striated muscle fibrils.
Industry:Health care
1) The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4. 2) Any of the repeating globular subunits of chromatin that consist of a complex of DNA and histone and are thought to be present only during interphase. 3) A nucleosome is the basic repeating unit of eukaryotic chromatin. In a human cell, about six feet of DNA must be packaged into a nucleus with a diameter less than a human hair. A single nucleosome consists of about 150 base pairs of DNA sequence wrapped around a core of histone proteins. The nucleosomes are arranged like beads on a string. They are repeatedly folded in on themselves to form a chromosome.
Industry:Health care
1) The reproductive cells in multicellular organisms. 2) Gametes, also known as sex cells or germ cells, are the cells that come together during fertilization or conception in organisms that reproduce sexually. Their genetic complement consists of a single set of unpaired chromosomes. (from Wikipedia) 3) Mature male or female reproductive cell (sperm or ovum) with a haploid set of chromosomes (23 for humans). 4) A reproductive cell of the body. Germ cells are egg cells in females and sperm cells in males.
Industry:Health care
1) The second phase of mitosis, in which the chromosomes line up across the equatorial plane of the spindle prior to separation. 2) A stage in mitosis or meiosis during which the chromosomes are aligned along the equatorial plane of the cell. 3) Metaphase is a stage during the process of cell division (mitosis or meiosis). Usually, individual chromosomes cannot be observed in the cell nucleus. However, during metaphase of mitosis or meiosis the chromosomes condense and become distinguishable as they align in the center of the dividing cell. Metaphase chromosomes are used during the karyotyping procedure that is used to look for chromosomal abnormalities.
Industry:Health care
1) The segment at the end of each chromosome arm which consists of a series of repeated DNA sequences that regulate chromosomal replication at each cell division. Some of the telomere is lost each time a cell divides, and eventually, when the telomere is gone, the cell dies. 2) The natural end of a eukaryotic chromosome composed of a usually repetitive DNA sequence and serving to stabilize the chromosome. 3) A telomere is the end of a chromosome. Telomeres are made of repetitive sequences of non-coding DNA that protect the chromosome from damage. Each time a cell divides, the telomeres become shorter. Eventually, the telomeres become so short that the cell can no longer divide.
Industry:Health care
1) The sensation or perception of scents or odors. 2) Smell; the faculty of smell, the sensation that results when olfactory receptors in the nose are stimulated by particular chemicals in gaseous form.
Industry:Health care
1) The separation of proteins on an electrophoretic gel for identification by immunological techniques. 2) Western blotting is a laboratory technique used to detect a specific protein in a blood or tissue sample. The method involves using gel electrophoresis to separate the sample's proteins. The separated proteins are transferred out of the gel to the surface of a membrane. The membrane is exposed to an antibody specific to the target protein. Binding of the antibody is detected using a radioactive or chemical tag. A western blot is sometimes used to diagnose disease.
Industry:Health care
1) The separation of sequences or fragments of RNA, partially digested by endonucleases, on an electrophoretic gel. 2) A blot consisting of a sheet of cellulose nitrate or nylon that contains spots of RNA for identification by a suitable molecular probe. 3) Northern blot is a laboratory technique used to detect a specific RNA sequence in a blood or tissue sample. The sample RNA molecules are separated by size using gel electrophoresis. The RNA fragments are transferred out of the gel to the surface of a membrane. The membrane is exposed to a DNA probe labeled with a radioactive or chemical tag. If the probe binds to the membrane, then the complementary RNA sequence is present in the sample.
Industry:Health care
1) The separation of substances in solution by means of their unequal diffusion through semipermeable membranes; especially: such a separation of colloids from soluble substances. 2) Either of two medical procedures to remove wastes or toxins from the blood and adjust fluid and electrolyte imbalances by utilizing rates at which substances diffuse through a semipermeable membrane: a) the process of removing blood from an artery (as of a kidney patient), purifying it by dialysis, adding vital substances, and returning it to a vein--called also hemodialysis, b) a procedure performed in the peritoneal cavity in which the peritoneum acts as the semipermeable membrane--called also peritoneal dialysis.
Industry:Health care
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