1) An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.

2) Any enzyme (as one secreted by the pancreas) that catalyzes the breakdown of fats and lipoproteins usually into fatty acids and glycerol.