Home > Term: comet assay
comet assay
Means of measuring DNA damage, particularly DNA strand breaks. A cell is embedded in agar and exposed to a DNA-damaging agent. The cell is then permeabilized with a detergent and an electric field is applied. If the cell's genomic DNA has been broken into small fragments, these fragments move out of the cell by electrophoresis and form a streak or “tail” leading away from the cell which looks like a comet.
- Kalbos dalis: noun
- Pramonės šaka / sritis: Biology; Chemistry
- Category: Toxicology
- Company: National Library of Medicine
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- Walter Lane
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