- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) The separation of the homologous chromosomes and their random distribution to the gametes at meiosis.
2) The separation of allelic genes that occurs typically during meiosis.
Industry:Health care
1) The separation on an electrophoretic gel of sequences or fragments of genomic or complementary DNA, partially digested by endonucleases, The fragments are then 'blotted' onto a membrane and allowed to hybridize with a specific, labeled probe in order to detect which bands contain the fragment or gene of interest. Southern blot is particularly useful in detecting large gene rearrangements/deletions and large trinucleotide repeat expansions.
2) Southern blotting is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample. A restriction enzyme is used to cut a sample of DNA into fragments that are separated using gel electrophoresis. The DNA fragments are transferred out of the gel to the surface of a membrane. The membrane is exposed to a DNA probe labeled with a radioactive or chemical tag. If the probe binds to the membrane, then the probe sequence is present in the sample.
Industry:Health care
1) The sequence of purines and pyrimidines in nucleic acids and polynucleotides. It is also called nucleotide sequence.
2) Order of purines and pyrimidines in nucleic acids and polynucleotides.
3) The order of nucleotide bases in a DNA molecule.
4) The order of nucleotide bases in a DNA molecule; determines structure of proteins encoded by that DNA.
Industry:Health care
1) The shell-like structure projects like a little wing (pinna) from the side of the head. Ear auricles collect sound from the environment.
2) The largely cartilaginous projecting portion of the external ear.
Industry:Health care
1) The small RNA molecules, 73-80 nucleotides long, that function during translation to align amino acids at the ribosomes in a sequence determined by the mRNA. There are about 30 different transfer RNAs. Each recognizes a specific codon set on the mRNA through its own anticodon, and as aminoacyl tRNAs, each carries a specific amino acid to the ribosome to add to the elongating peptide chains.
2) A class of RNA having structures with triplet nucleotide sequences that are complementary to the triplet nucleotide coding sequences of mRNA. The role of tRNAs in protein synthesis is to bond with amino acids and transfer them to the ribosomes, where proteins are assembled according to the genetic code carried by mRNA.
3) A relatively small RNA that transfers a particular amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation -- called also adapter RNA, soluble RNA, tRNA.
4) Transfer RNA (tRNA) is a small RNA molecule that participates in protein synthesis. Each tRNA molecule has two important areas: a trinucleotide region called the anticodon and a region for attaching a specific amino acid. During translation, each time an amino acid is added to the growing chain, a tRNA molecule forms base pairs with its complementary sequence on the messenger RNA (mRNA) molecule, ensuring that the appropriate amino acid is inserted into the protein.
Industry:Health care
1) The smallest units of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid. Cells are highly variable and specialized in both structure and function, though all must at some stage replicate proteins and nucleic acids, utilize energy, and reproduce themselves.
2) A cell is the basic building block of living things. All cells can be sorted into one of two groups: eukaryotes and prokaryotes. A eukaryote has a nucleus and membrane-bound organelles, while a prokaryote does not. Plants and animals are made of numerous eukaryotic cells, while many microbes, such as bacteria, consist of single cells. An adult human body is estimated to contain between 10 and 100 trillion cells.
Industry:Health care
1) The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
2) The soft, sponge-like tissue in the center of bones that produces white blood cells, red blood cells, and platelets.
Industry:Health care
1) The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
2) The soft, sponge-like tissue in the center of bones that produces white blood cells, red blood cells, and platelets.
Industry:Health care
1) The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation.
2) A state of partial contraction that is characteristic of normal muscle, is maintained at least in part by a continuous bombardment of motor impulses originating reflexly, and serves to maintain body posture.
Industry:Health care
1) The study of hearing and hearing impairment.
2) A branch of science dealing with hearing; specifically: therapy of individuals having impaired hearing.
Industry:Health care