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United States National Library of Medicine
Industry: Library & information science
Number of terms: 152252
Number of blossaries: 0
Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by autoimmune diseases. 2) A condition in which the body produces an immune response against its own tissue constituents.
Industry:Health care
1) Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible. 2) A stage of meiotic prophase immediately preceding synapsis in which the chromosomes appear as fine discrete threads.
Industry:Health care
1) Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome. 2) The stage of meiotic prophase which immediately follows the zygotene and in which the paired chromosomes are thickened and visibly divided into chromatids.
Industry:Health care
1) Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of myotonic disorders. 2) Tonic spasm of one or more muscles; also: a condition characterized by such spasms.
Industry:Health care
1) Proteases which use a metal, normally zinc, in the catalytic mechanism. This group of enzymes is inactivated by metal chelators. 2) Encoded by metalloproteinase genes, metalloproteinases (endopeptidases) use a metal ion, normally zinc, in the catalytic process and preferentially cleave the Gln-Gly peptide bond. Metalloproteinases inactivated by metal chelators.
Industry:Health care
1) Protein components of lipoproteins which remain after the lipids to which the proteins are bound have been removed; they play an important role in lipid transport and metabolism. 2) The protein component of lipoproteins. 3) Any of the proteins that combine with a lipid to form a lipoprotein and that are now grouped into four classes designated A, B, C, and E and formerly into a fifth class D now considered part of A -- often followed by the letter designating the class or by the letter and a number expressed in Roman or Arabic numerals to indicate a specific member of the class (apolipoprotein B is a major component of LDL).
Industry:Health care
1) Proteins that contain phosphate groups esterified to serine, threonine or tyrosine. The phosphate group usually regulates protein function. 2) Any of various proteins (as casein) that contain combined phosphoric acid.
Industry:Health care
1) Protozoan disease caused in humans by four species of the genus Plasmodium (P. falciparum, P. vivax, P. ovale, and P. malariae) and transmitted by the bite of an infected female mosquito of the genus Anopheles; malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands; characterized by extreme exhaustion associated with paroxysms of high fever, sweating, shaking chills, and anemia; malaria in animals is caused by other species of plasmodia. 2) An acute or chronic disease caused by the presence of sporozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle <malaria remains the greatest single cause of debilitation and death throughout the world -- Journal of the American Medical Association>. 2) Any of various diseases of birds and mammals that are more or less similar to malaria of human beings and are caused by blood protozoans.
Industry:Health care
1) Protruding sac in the wall of a vein, artery, or heart, frequently caused by microbial infection; may present as pain, pressure on nearby organs, or cardiac weakening. 2) A sac formed by the dilatation of the wall of an artery, a vein, or the heart. 3) An abnormal blood-filled dilatation of a blood vessel and especially an artery resulting from disease of the vessel wall.
Industry:Health care
1) Protrusion of a loop or knuckle of an organ or tissue through an abnormal opening. 2) A protrusion of an organ or part through connective tissue or through a wall of the cavity in which it is normally enclosed -- called also rupture.
Industry:Health care
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