- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (neurofibrillary tangles; neurophil threads) in numerous neurodegenerative disorders (Alzheimer disease; tauopathies).
2) Family of structural proteins of microtubules which serve to crosslink and therefore stabilize tubulin chains.
3) A protein that binds to and regulates the assembly and stability of neuronal microtubules and that is found in an abnormal form as the major component of neurofibrillary tangles.
Industry:Health care
1) Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (neurofibrillary tangles; neurophil threads) in numerous neurodegenerative disorders (Alzheimer disease; tauopathies).
2) Family of structural proteins of microtubules which serve to crosslink and therefore stabilize tubulin chains.
3) A protein that binds to and regulates the assembly and stability of neuronal microtubules and that is found in an abnormal form as the major component of neurofibrillary tangles.
Industry:Health care
1) Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.
2) A microorganism that can infect cells and cause disease.
3) A virus is an infectious agent that occupies a place near the boundary between the living and the nonliving. It is a particle much smaller than a bacterial cell, consisting of a small genome of either DNA or RNA surrounded by a protein coat. Viruses enter host cells and hijack the enzymes and materials of the host cells to make more copies of themselves. Viruses cause a wide variety of diseases in plants and animals, including AIDS, measles, smallpox, and polio.
Industry:Health care
1) Minute projections of cell membranes which greatly increase the surface area of the cell.
2) A microscopic projection of a tissue, cell, or cell organelle; especially : any of the fingerlike outward projections of some cell surfaces.
Industry:Health care
1) Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
2) A drug used to treat depression.
Industry:Health care
1) MRI. A procedure in which a magnet linked to a computer is used to create detailed pictures of areas inside the body. Also called nuclear magnetic resonance imaging.
2) A noninvasive diagnostic technique that produces computerized images of internal body tissues and is based on nuclear magnetic resonance of atoms within the body induced by the application of radio waves -- called also MRI.
Industry:Health care
1) Mucus-secreting membrane lining all body cavities or passages that communicate with the exterior.
2) The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
Industry:Health care
1) Multiple, often seemingly unrelated, physical effects caused by a single altered gene or pair of altered genes.
2) The phenomenon of variable phenotypes for a number of distinct and seemingly unrelated phenotypic effects.
3) Producing more than one effect; especially : having multiple phenotypic expressions <a pleiotropic gene>.
Industry:Health care
1) Multiple, often seemingly unrelated, physical effects caused by a single altered gene or pair of altered genes.
2) The phenomenon of variable phenotypes for a number of distinct and seemingly unrelated phenotypic effects.
3) Producing more than one effect; especially : having multiple phenotypic expressions <a pleiotropic gene>.
Industry:Health care
1) Natural evolutionary process that results in the survival of organisms best suited to changing living conditions through the perpetuation of desirable genetic qualities and the elimination of undesirable ones.
2) A natural process that results in the survival and reproductive success of individuals or groups best adjusted to their environment and that leads to the perpetuation of genetic qualities best suited to that particular environment.
Industry:Health care
