- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from cranial nerve diseases, neuromuscular diseases, cerebellar diseases, basal ganglia diseases, brain stem diseases, or diseases of the corticobulbar tracts. The cortical language centers are intact in this condition.
2) Articulation disorder resulting from central nervous system disease, especially brain damage.
3) Difficulty in articulating words due to disease of the central nervous system.
Industry:Health care
1) Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from cranial nerve diseases, neuromuscular diseases, cerebellar diseases, basal ganglia diseases, brain stem diseases, or diseases of the corticobulbar tracts. The cortical language centers are intact in this condition.
2) Articulation disorder resulting from central nervous system disease, especially brain damage.
3) Difficulty in articulating words due to disease of the central nervous system.
Industry:Health care
1) DNA artificially constructed by combining genes from different organisms or by cloning chemically altered DNA, usually for the purpose of genetic manipulation.
2) Genetically engineered DNA usually incorporating DNA from more than one species of organism.
3) Recombinant DNA (rDNA) is a technology that uses enzymes to cut and paste together DNA sequences of interest. The recombined DNA sequences can be placed into vehicles called vectors that ferry the DNA into a suitable host cell where it can be copied or expressed.
Industry:Health care
1) DNA constructs that are composed of, at least, a replication origin, for successful replication, propagation to and maintenance as an extra chromosome in bacteria. In addition, they can carry large amounts (about 200 kilobases) of other sequence for a variety of bioengineering purposes.
2) A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are often used in connection with DNA sequencing. Segments of an organism's DNA, ranging from 100,000 to about 300,000 base pairs, can be inserted into BACs. The BACs, with their inserted DNA, are then taken up by bacterial cells. As the bacterial cells grow and divide, they amplify the BAC DNA, which can then be isolated and used in sequencing DNA.
Industry:Health care
1) DNA repair genes encode DNA repair proteins, involved in enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage. (NCI)
2) Genes encoding proteins that correct errors in DNA sequencing.
3) Certain genes that are part of a DNA repair pathway; when altered, they permit mutations to pile up throughout the DNA.
Industry:Health care
1) DNA repair genes encode DNA repair proteins, involved in enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage. (NCI)
2) Genes encoding proteins that correct errors in DNA sequencing.
3) Certain genes that are part of a DNA repair pathway; when altered, they permit mutations to pile up throughout the DNA.
Industry:Health care
1) Double-strand, closed DNA molecules found in cytoplasm of a variety of bacterial species that generally confer some evolutionary advantage to the host cells.
2) An extrachromosomal ring of DNA that replicates autonomously and is found especially in bacteria.
3) A plasmid is a small, often circular DNA molecule found in bacteria and other cells. Plasmids are separate from the bacterial chromosome and replicate independently of it. They generally carry only a small number of genes, notably some associated with antibiotic resistance. Plasmids may be passed between different bacterial cells.
Industry:Health care
1) Drug or radiation effects on DNA that interfere with normal function, including conformational distortions and covalent gene mutations.
2) Drug- or radiation-induced injuries in DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA REPAIR). If the damage is extensive, it can induce apoptosis.
Industry:Health care
1) Drug or radiation effects on DNA that interfere with normal function, including conformational distortions and covalent gene mutations.
2) Drug- or radiation-induced injuries in DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA REPAIR). If the damage is extensive, it can induce apoptosis.
Industry:Health care
1) Ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
2) A gland (as the thyroid or the pituitary) that produces an endocrine secretion -- called also ductless gland, gland of internal secretion.
Industry:Health care
