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United States National Library of Medicine
Industry: Library & information science
Number of terms: 152252
Number of blossaries: 0
Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature. 2) A specialized local thickening of the plasma membrane of an epithelial cell that serves to anchor contiguous cells together.
Industry:Health care
1) Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature. 2) A specialized local thickening of the plasma membrane of an epithelial cell that serves to anchor contiguous cells together.
Industry:Health care
1) Different forms of a protein that may be produced from different genes, or from the same gene by alternative splicing. 2) The protein products of different versions of messenger RNA created from the same gene by employing different promoters, which causes transcription to skip certain exons. Since the promoters are tissue-specific, different tissues express different protein products of the same gene.
Industry:Health care
1) Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population. 2) The process of determining the relative share allotted individuals of different genotypes in the propagation of a population; the selective effect of a gene can be defined by the probability that carriers of the gene will reproduce.
Industry:Health care
1) Difficult or labored breathing. 2) Labored or difficult breathing associated with a variety of disorders, indicating inadequate ventilation or low blood oxygen.
Industry:Health care
1) Difficult or labored breathing. 2) Labored or difficult breathing associated with a variety of disorders, indicating inadequate ventilation or low blood oxygen.
Industry:Health care
1) Difficulty in swallowing which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the pharynx and upper esophageal sphincter; and esophageal dysphagia due to malfunction of the esophagus. 2) Difficulty swallowing.
Industry:Health care
1) Diminution or disappearance of symptoms. 2) An abatement in intensity or degree (as in the manifestations of a disease). 3) A state or period during which the symptoms of a disease are abated <cancer in remission after treatment>.
Industry:Health care
1) Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc. 2) The group of applied techniques of genetics and biotechnology used to cut up and join together genetic material and especially DNA from one or more species of organism and to introduce the result into an organism in order to change one or more of its characteristics. 3) Procedure used to join together DNA segments in a cell-free system (an environment outside a cell or organism). Under appropriate conditions, a recombinant DNA molecule can enter a cell and replicate there, either autonomously or after it has become integrated into a cellular chromosome. 4) Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism. Traditionally, humans have manipulated genomes indirectly by controlling breeding and selecting offspring with desired traits. Genetic engineering involves the direct manipulation of one or more genes. Most often, a gene from another species is added to an organism's genome to give it a desired phenotype.
Industry:Health care
1) Disorder of cardiac rhythm characterized by rapid, irregular atrial impulses and ineffective atrial contractions. 2) Very rapid uncoordinated contractions of the atria of the heart resulting in a lack of synchronism between heartbeat and pulse beat -- called also auricular fibrillation.
Industry:Health care
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