- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) An identical copy of a DNA sequence or entire gene; one or more cells derived from and identical to a single ancestor cell; to isolate a gene or specific sequence of DNA.
2) An exact copy made of biological material such as a DNA segment (e.g., a gene or other region), a whole cell, or a complete organism.
Industry:Health care
1) An identifiable segment of DNA (e.g., RFLP, VNTR, microsatellite) with enough variation between individuals that its inheritance and co-inheritance with alleles of a given gene can be traced; used in linkage analysis.
2) A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes. DNA segments close to each other on a chromosome tend to be inherited together. Markers are used to track the inheritance of a nearby gene that has not yet been identified but whose approximate location is known. The marker itself may be a part of a gene or may have no known function.
Industry:Health care
1) An identifiable segment of DNA (e.g., RFLP, VNTR, microsatellite) with enough variation between individuals that its inheritance and co-inheritance with alleles of a given gene can be traced; used in linkage analysis.
2) A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes. DNA segments close to each other on a chromosome tend to be inherited together. Markers are used to track the inheritance of a nearby gene that has not yet been identified but whose approximate location is known. The marker itself may be a part of a gene or may have no known function.
Industry:Health care
1) An immune system cell that can surround and kill microorganisms and remove dead cells. Phagocytes include macrophages.
2) A cell (as a white blood cell) that engulfs and consumes foreign material (as microorganisms) and debris.
Industry:Health care
1) An increase in the number of haploid sets (23) of chromosomes in a cell. Triploidy refers to three whole sets of chromosomes in a single cell (in humans, a total of 69 chromosomes per cell); tetraploidy refers to four whole sets of chromosomes in a single cell (in humans, a total of 92 chromosomes per cell).
2) Having or being a chromosome number that is a multiple greater than two of the monoploid number.
Industry:Health care
1) An increase in the number of haploid sets (23) of chromosomes in a cell. Triploidy refers to three whole sets of chromosomes in a single cell (in humans, a total of 69 chromosomes per cell); tetraploidy refers to four whole sets of chromosomes in a single cell (in humans, a total of 92 chromosomes per cell).
2) Having or being a chromosome number that is a multiple greater than two of the monoploid number.
Industry:Health care
1) An indication that a person has a condition or disease. Some examples of symptoms are headache, fever, fatigue, nausea, vomiting, and pain.
2) Subjective evidence of disease or physical disturbance observed by the patient <headache is a symptom of many diseases> <visual disturbances may be a symptom of retinal arteriosclerosis>; broadly: something that indicates the presence of a physical disorder.
Industry:Health care
1) An individual who has a recessive, disease-causing allele at a particular locus on one chromosome of a pair and a normal allele at that locus on the other chromosome.
2) A carrier is an individual who carries and is capable of passing on a genetic mutation associated with a disease and may or may not display disease symptoms. Carriers are associated with diseases inherited as recessive traits. In order to have the disease, an individual must have inherited mutated alleles from both parents. An individual having one normal allele and one mutated allele does not have the disease. Two carriers may produce children with the disease.
Industry:Health care
1) An inherited characteristic.
2) Any detectable phenotypic property of an organism.
3) A trait is a specific characteristic of an organism. Traits can be determined by genes or the environment, or more commonly by interactions between them. The genetic contribution to a trait is called the genotype. The outward expression of the genotype is called the phenotype.
Industry:Health care
1) An insertion or deletion involving a number of base pairs that is not a multiple of three and consequently disrupts the triplet reading frame, usually leading to the creation of a premature termination (stop) codon and resulting in a truncated protein product.
2) A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three. "Divisible by three" is important because the cell reads a gene in groups of three bases. Each group of three bases corresponds to one of 20 different amino acids used to build a protein. If a mutation disrupts this reading frame, then the entire DNA sequence following the mutation will be read incorrectly.
Industry:Health care
