- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
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The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) A reaction of donated stem cells against the patient's tissue.
2) A bodily condition that results when T cells from a usually allogeneic tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues, that affects especially the skin, gastrointestinal tract, and liver with symptoms including skin rash, fever, diarrhea, liver dysfunction, abdominal pain, and anorexia, and that may be fatal -- abbreviation GVHD; called also graft-versus-host reaction.
Industry:Health care
1) A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain.
2) A reading frame that does not contain a nucleotide triplet which stops translation before formation of a complete polypeptide -- abbreviation ORF.
3) An open reading frame is a portion of a DNA molecule that, when translated into amino acids, contains no stop codons. The genetic code reads DNA sequences in groups of three base pairs, which means that a double-stranded DNA molecule can read in any of six possible reading frames--three in the forward direction and three in the reverse. A long open reading frame is likely part of a gene.
Industry:Health care
1) A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain.
2) A reading frame that does not contain a nucleotide triplet which stops translation before formation of a complete polypeptide -- abbreviation ORF.
3) An open reading frame is a portion of a DNA molecule that, when translated into amino acids, contains no stop codons. The genetic code reads DNA sequences in groups of three base pairs, which means that a double-stranded DNA molecule can read in any of six possible reading frames--three in the forward direction and three in the reverse. A long open reading frame is likely part of a gene.
Industry:Health care
1) A reduction in the number of circulating erythrocytes or in the quantity of hemoglobin.
2) A condition in which the number of red blood cells is below normal.
Industry:Health care
1) A relatively common neoplasm of the central nervous system that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and spinal canal. They tend to present in the fourth to sixth decades of life with signs indicative of a slowly progressive mass lesion. Specific clinical manifestations depend on the location of the tumor, but may include intracranial hypertension, cranial neuropathies, ataxia, and other focal neurologic signs. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
2) A slow-growing encapsulated tumor arising from the meninges and often causing damage by pressing upon the brain and adjacent parts.
3) A type of tumor that occurs in the meninges, the membranes that cover and protect the brain and spinal cord. Meningiomas usually grow slowly.
Industry:Health care
1) A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
2) A mass or nodule of chronically inflamed tissue with granulations that is usually associated with an infective process.
Industry:Health care
1) A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
2) A mass or nodule of chronically inflamed tissue with granulations that is usually associated with an infective process.
Industry:Health care
1) A restriction enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences. The isolation of these enzymes was critical to the development of recombinant DNA (rDNA) technology and genetic engineering.
2) A protein that recognizes specific, short nucleotide sequences and cuts DNA at those sites. Bacteria contain over 400 such enzymes that recognize and cut more than 100 different DNA sequences.
Industry:Health care
1) A restriction enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences. The isolation of these enzymes was critical to the development of recombinant DNA (rDNA) technology and genetic engineering.
2) A protein that recognizes specific, short nucleotide sequences and cuts DNA at those sites. Bacteria contain over 400 such enzymes that recognize and cut more than 100 different DNA sequences.
Industry:Health care
1) A retrovirus is a virus that uses RNA as its genetic material. When a retrovirus infects a cell, it makes a DNA copy of its genome that is inserted into the DNA of the host cell. There are a variety of different retroviruses that cause human diseases, including the common cold, some forms of cancer, and AIDS.
2) A type of virus that has RNA instead of DNA as its genetic material. It uses an enzyme called reverse transcriptase to become part of the host cells' DNA. This allows many copies of the virus to be made in the host cells. The virus that causes AIDS, the human immunodeficiency virus (HIV), is a type of retrovirus.
Industry:Health care
