- Industry: Library & information science
- Number of terms: 152252
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The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) A membranous and usually fluid-filled pouch (as a cyst, vacuole, or cell) in a plant or animal.
2) A small abnormal elevation of the outer layer of skin enclosing a watery liquid: blister.
3) A pocket of embryonic tissue that is the beginning of an organ.
Industry:Health care
1) A metacentric chromosome produced during mitosis or meiosis when the centromere splits transversely instead of longitudinally; the arms of such chromosome are equal in length and genetically identical, however, the loci are positioned in reverse sequence in the two arms.
2) A chromosome produced by transverse splitting of the centromere so that both arms are from the same side of the centromere, are of equal length, and possess identical genes.
Industry:Health care
1) A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It has the atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia. (From Dorland, 27th ed)
2) A heavy malleable ductile magnetic silver-white metallic element that readily rusts in moist air, occurs native in meteorites and combined in most igneous rocks, is the most used of metals, and is vital to biological processes (as in transport of oxygen in the body) -- symbol Fe.
3) Iron chemically combined <iron in the blood>.
Industry:Health care
1) A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It has the atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia. (From Dorland, 27th ed)
2) A heavy malleable ductile magnetic silver-white metallic element that readily rusts in moist air, occurs native in meteorites and combined in most igneous rocks, is the most used of metals, and is vital to biological processes (as in transport of oxygen in the body) -- symbol Fe.
3) Iron chemically combined <iron in the blood>.
Industry:Health care
1) A method employed to determine differences in amino acid sequences between related proteins; relies upon the presence of a simple tandem-repetitive sequences that are scattered throughout the human genome.
2) A technique used especially for identification (as for forensic purposes) by extracting and identifying the base-pair pattern of an individual's DNA -- called also DNA typing, genetic fingerprinting.
3) DNA fingerprinting is a laboratory technique used to establish a link between biological evidence and a suspect in a criminal investigation. A DNA sample taken from a crime scene is compared with a DNA sample from a suspect. If the two DNA profiles are a match, then the evidence came from that suspect. Conversely, if the two DNA profiles do not match, then the evidence cannot have come from the suspect. DNA fingerprinting is also used to establish paternity.
Industry:Health care
1) A method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules. An electric current is passed through a medium containing the mixture, and each kind of molecule travels through the medium at a different rate, depending on its electrical charge and size. Agarose and acrylamide gels are the media commonly used for electrophoresis of proteins and nucleic acids.
2) Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules based on their size and electrical charge. An electric current is used to move molecules to be separated through a gel. Pores in the gel work like a sieve, allowing smaller molecules to move faster than larger molecules. The conditions used during electrophoresis can be adjusted to separate molecules in a desired size range.
Industry:Health care
1) A minute reddish or purplish spot containing blood that appears in skin or mucous membrane as a result of localized hemorrhage.
2) Pinpoint, unraised, round red spots under the skin caused by bleeding.
Industry:Health care
1) A molecule (as a short strand of RNA or DNA) whose presence is required for formation of another molecule (as a longer chain of DNA).
2) Short preexisting polynucleotide chain to which new deoxyribonucleotides can be added by DNA polymerase.
3) A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique. In the PCR method, a pair of primers is used to hybridize with the sample DNA and define the region of the DNA that will be amplified. Primers are also referred to as oligonucleotides.
Industry:Health care
1) A molecule consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate group, and a sugar (deoxyribose in DNA; ribose in RNA). DNA and RNA are polymers of many nucleotides.
2) A nucleotide is the basic building block of nucleic acids. RNA and DNA are polymers made of long chains of nucleotides. A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base. The bases used in DNA are adenine (A), cytosine (C), guanine (G), and thymine (T). In RNA, the base uracil (U) takes the place of thymine.
3) A subunit of DNA or RNA, consisting of one chemical base plus a phosphate molecule and a sugar molecule.
Industry:Health care
1) A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies.
2) A large molecule composed of one or more chains of amino acids in a specific order; the order is determined by the base sequence of nucleotides in the gene that codes for the protein. Proteins are required for the structure, function, and regulation of the body's cells, tissues, and organs; and each protein has unique functions. Examples are hormones, enzymes, and antibodies.
3) Proteins are an important class of molecules found in all living cells. A protein is composed of one or more long chains of amino acids, the sequence of which corresponds to the DNA sequence of the gene that encodes it. Proteins play a variety of roles in the cell, including structural (cytoskeleton), mechanical (muscle), biochemical (enzymes), and cell signaling (hormones). Proteins are also an essential part of diet.
Industry:Health care
