- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
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The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) A grouping of things based on shared common attributes.
2) A group, set, or kind marked by common attributes or a common attribute; especially : a major category in biological taxonomy ranking above the order and below the phylum or division (the class Mammalia).
Industry:Health care
1) A haplotype is a set of DNA variations, or polymorphisms, that tend to be inherited together. A haplotype can refer to a combination of alleles or to a set of single nucleotide polymorphisms (SNPs) found on the same chromosome. Information about haplotypes is being collected by the International HapMap Project and is used to investigate the influence of genes on disease.
2) A group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit.
Industry:Health care
1) A heteropolysaccharide that is similar in structure to heparin. It accumulates in individuals with mucopolysaccharidosis.
2) similar to heparin but with some L-iduronic acid residues.
3) Heparitin Sulfate. A glycosaminoglycan, structurally similar to heparin but with more N-acetyl groups and fewer O- and N-sulfate groups. Occurs in the liver, aorta, and lung. Accumulates in several mucopolysaccharidoses.
Industry:Health care
1) A heteropolysaccharide that is similar in structure to heparin. It accumulates in individuals with mucopolysaccharidosis.
2) similar to heparin but with some L-iduronic acid residues.
3) Heparitin Sulfate. A glycosaminoglycan, structurally similar to heparin but with more N-acetyl groups and fewer O- and N-sulfate groups. Occurs in the liver, aorta, and lung. Accumulates in several mucopolysaccharidoses.
Industry:Health care
1) A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular protein transport and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
2) Ubiquitous intracellular protein which, when covalently attached to other proteins, marks them for degradation or targeted transport.
3) A family of proteins found in all cells of higher organisms and one whose structure has changed minimally during evolutionary history. It is involved in at least two processes; histone modification and intracellular protein breakdown. Ubiquitin-dependent proteolysis by the 26S proteasome plays a pivotal role in cell cycle progression as well as in tumorigenesis. It is encoded by at least three genes; UBB, UBC and UBD.
Industry:Health care
1) A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
2) blood deficiency in an organ or tissue caused by a constriction or obstruction of its blood vessels.
Industry:Health care
1) A large molecule composed of nucleotide subunits.
2) Any of various acids (as an RNA or a DNA) composed of nucleotide chains.
3) Nucleic acid is an important class of macromolecules found in all cells and viruses. The functions of nucleic acids have to do with the storage and expression of genetic information. Deoxyribonucleic acid (DNA) encodes the information the cell needs to make proteins. A related type of nucleic acid, called ribonucleic acid (RNA), comes in different molecular forms that participate in protein synthesis.
Industry:Health care
1) A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
2) A break in skin or mucous membrane with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus.
3) A break on the skin, in the lining of an organ, or on the surface of a tissue. An ulcer forms when the surface cells become inflamed, die, and are shed. Ulcers may be linked to cancer and other diseases.
Industry:Health care
1) A light-sensitive neuroendocrine organ attached to the roof of the third ventricle of the brain. The pineal gland secretes melatonin, other biogenic amines, and neuropeptides.
2) A small body that arises from the roof of the third ventricle and is enclosed by the pia mater and that functions primarily as an endocrine gland that produces melatonin -- called also pineal, pineal body, pineal organ.
3) A tiny organ in the cerebrum that produces melatonin.
Industry:Health care
1) A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
2) Any of several mood disorders characterized usually by alternating episodes of depression and mania or by episodes of depression alternating with mild nonpsychotic excitement -- called also bipolar affective disorder, bipolar illness, manic depression, manic-depressive psychosis.
Industry:Health care
