- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) A disease in which the metabolic products of phenylalanine and tyrosine accumulate, resulting in the deposition of homogentisic acid (a brown-black pigment) in the connective tissue. It occurs in alkaptonuria, but has also been observed in connection with exposure to certain chemicals (e.g., phenol, trinitrophenol, benzene derivatives).
2) A condition often associated with alkaptonuria and marked by pigment deposits in cartilages, ligaments, and tendons.
Industry:Health care
1) A disease in which the metabolic products of phenylalanine and tyrosine accumulate, resulting in the deposition of homogentisic acid (a brown-black pigment) in the connective tissue. It occurs in alkaptonuria, but has also been observed in connection with exposure to certain chemicals (e.g., phenol, trinitrophenol, benzene derivatives).
2) A condition often associated with alkaptonuria and marked by pigment deposits in cartilages, ligaments, and tendons.
Industry:Health care
1) A disease of the skin marked by overgrowth of horny tissue.
2) An area of the skin affected with keratosis.
Industry:Health care
1) A disorder affecting the cranial nerves or the peripheral nervous system. It is manifested with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs. -- 2004
2) An abnormal and usually degenerative state of the nervous system or nerves; also, a systemic condition (as muscular atrophy) that stems from a neuropathy.
Industry:Health care
1) A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-IV)
2) A developmental disorder that appears by age three and that is variable in expression but is recognized and diagnosed by impairment of the ability to form normal social relationships, by impairment of the ability to communicate with others, and by stereotyped behavior patterns especially as exhibited by a preoccupation with repetitive activities of restricted focus rather than with flexible and imaginative ones.
3) Autism is a developmental brain disorder characterized by impaired social interactions, communication problems, and repetitive behaviors. Symptoms usually appear before the age of three. The exact cause of autism is not known, however, it is likely influenced by genetics. Autism is one of a group of related developmental disorders called autism spectrum disorders (ASDs). Other ASDs include Asperger syndrome and Rett syndrome.
Industry:Health care
1) A disorder characterized by persistent developmentally inappropriate inattention and impulsivity.
2) A syndrome of disordered learning and disruptive behavior that is not caused by any serious underlying physical or mental disorder and that has several subtypes characterized primarily by symptoms of inattentiveness or primarily by symptoms of hyperactivity and impulsive behavior (as in speaking out of turn) or by the significant expression of all three -- abbreviation ADD; called also minimal brain dysfunction.
Industry:Health care
1) A disorder characterized by the presence of anemia, abnormally large red blood cells (megalocytes or macrocytes), and megaloblasts.
2) An anemia (as pernicious anemia) characterized by the presence of megaloblasts in the circulating blood.
Industry:Health care
1) A disorder of hemostasis in which there is a tendency for the occurrence of thrombosis.
2) A hereditary or acquired predisposition to thrombosis.
Industry:Health care
1) A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2) Any of a class of usually insoluble cellular protein fibers (as a neurofilament or an epithelial-cell cytoplasmic filament of keratin) composed of various fibrous polypeptides that serve especially to provide structural stability and strength to the cytoskeleton and are intermediate in diameter between microfilaments and microtubules.
Industry:Health care
1) A diverse family of extracellular (e.g., laminin) and cell surface (e.g., NCAM) glycoproteins involved in cell-cell and cell-extracellular matrix adhesion, recognition, activation, and migration.
2) Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.
Industry:Health care
