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United States National Library of Medicine
Industry: Library & information science
Number of terms: 152252
Number of blossaries: 0
Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
When a substance, such as a drug or solution, is introduced into the body through a route other than the gastrointestinal (GI) tract. (The GI tract extends from the mouth to the anus.) For example, a parenteral drug may be given through the veins (intravenous), into the muscles (intramuscular), or through the skin (subcutaneous). Parenteral nutrition refers to feeding a person intravenously.
Industry:Health care
When a tablet or capsule is coated with a substance that prevents the medication from being released until it reaches the small intestine, where it can then be absorbed.
Industry:Health care
When a virus is present in the body but exists in a resting (latent) state without producing more virus. A latent viral infection usually does not cause any noticeable symptoms and can last a long period of time before becoming active and causing symptoms. HIV is capable of viral latency, as seen in the reservoirs of latent HIV-infected cells that persist in a person’s body despite antiretroviral therapy (ART).
Industry:Health care
When an antiretroviral (ARV) regimen is unable to control HIV infection. Treatment failure can be clinical failure, immunologic failure, virologic failure, or any combination of the three. Factors that can contribute to treatment failure include drug resistance, drug toxicity, or poor treatment adherence.
Industry:Health care
When an HIV-infected mother passes HIV to her infant during pregnancy, labor and delivery, or breastfeeding (through breast milk). Antiretroviral (ARV) drugs are given to HIV-infected women during pregnancy and to their infants after birth to reduce the risk of mother-to-child transmission (MTCT) of HIV.
Industry:Health care
When an HIV-infected person converts from HIV negative to HIV positive by blood testing. Shortly after infection with HIV, the body begins to produce HIV antibodies. It takes the body a while to produce enough antibodies to be detected by an HIV antibody test—usually 10 to 14 days but sometimes up to 6 months. When HIV antibodies in the blood reach a detectable level, the HIV-infected person seroconverts. In other words, the person’s antibody test goes from HIV negative to HIV positive.
Industry:Health care
When an HIV-infected person has received antiretroviral (ARV) drugs from three drug classes—the nucleoside reverse transcriptase inhibitor (NRTI), non-nucleoside reverse transcriptase inhibitor (NNRTI), and protease inhibitor (PI) drug classes.
Industry:Health care
When an infection or disease has widely dispersed in a tissue, an organ, or the entire body.
Industry:Health care
When antiretroviral therapy (ART) reduces a person’s viral load (HIV RNA) to an undetectable level. Viral suppression does not mean a person is cured; HIV still remains in the body. If ART is discontinued, the person’s viral load will likely return to a detectable level.
Industry:Health care
When antiretroviral therapy (ART) reduces a person’s viral load (HIV RNA) to an undetectable level. Viral suppression does not mean a person is cured; HIV still remains in the body. If ART is discontinued, the person’s viral load will likely return to a detectable level.
Industry:Health care
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